To quote from (the Wayback version of) that page:

Why BioPerl is Fast

BLAST tiling in C++: development 1 mo. + analysis 5min;
BLAST tiling in BioPerl: development 2 d + analysis 30min.
(the reason cited for BioPerl running slowly is their use of inheritance)

In reply to Re^3: simple string comparison for efficiency by etj
in thread simple string comparison for efficiency by CaptainF

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