Sure, if you can exactly tell what the regex should accomplish -
split commas
except commas between quotes
except it's not between any quotes, but the quotes must be balanced
perhaps the quotes are nested
escaped quotes (\') have to be exempt
the same conditions for double quotes
them mixed and matched
what about escaped commas (\,)?
other special cases I forgot to think of?
I do use split sometimes, but only if it's guaranteed to be commas only. As soon as a special case becomes visible on the horizon, I use Text::CSV (which in turn uses Text::CSV_XS if possible).