Are these users logging into computers running Linux? If so, this probably a system security issue. If you need to layer application level access control on top of the system access controls, there are different possible ways to do this. More information is needed.
Is this a website running under Linux? If so, it is possible to create authentication and authorization modules for, at least, the Apache web server. The authentication module would verify the user's credentials and save a session record indicating which certificate(s) the user used. The authorization module would then use the information in the session record to grant/deny access to various resources provided through the web server.
Again, more information is needed.
Update: Fixed typos.
In reply to Re: Restricting access to Perl sacripts based on PKI certs
by RonW
in thread Restricting access to Perl sacripts based on PKI certs
by rgwest61
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