Examining @INC the usual way (like perl -E 'say for @INC;') shows these *nix-style paths

This would almost certainly indicate that the PATH environment variable is currently set such that the first perl.exe to be located is Cygwin's, not Strawberry's.
Next time this happens, run PATH to see what that environment variable actually contains ... and then try to work out why it changed.

Cheers,
Rob

In reply to Re^3: Strawberry Perl: my @INC gets/is destroyed on XP after some days by syphilis
in thread Strawberry Perl: my @INC gets/is destroyed on XP after some days by karlgoethebier

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