Also appears to be possible to override via http://docs.activestate.com/activeperl/5.20/lib/ActivePerl/Config.html#Windows-overrides 
set ACTIVEPERL_CONFIG_CC=cl
set ACTIVEPERL_CONFIG_MAKE=nmake
...

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In reply to Re^4: Change make/compiler by Anonymous Monk
in thread Activestate Perl 5.20, Change make/compiler by d.ra.ke

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