You might find this of interest: SQLite Locking.

SQLite has a robust locking mechanism. For a write, a connection has to acquire an exclusive lock on the DB. This can significantly affect the performance in multi-writer situations. Any failure in the locking mechanism would be a high priority bug.

In reply to Re^3: DBD::SQLite "file is encrypted or is not a database" in running application by Marshall
in thread [SOLVED]: DBD::SQLite "file is encrypted or is not a database" in running application by stevieb

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