No, primary reason to use sysread/syswrite with select, is because readline and print are not working with select.

Of course they do:

#! perl -sw
use strict;
use Win32::Socketpair qw[ winsocketpair ];

my( $fd1, $fd2 ) = winsocketpair();

my $v = '';
vec( $v, my $fn1 = fileno( $fd1 ), 1) = 1;
vec( $v, my $fn2 = fileno( $fd2 ), 1) = 1;

while( 1 ) {
    if( select( my $vin = $v, my $vout = $v, undef, undef ) > 0 ) {
        if( vec( $vout, $fn1, 1 ) ) {
            print( $fd1 "hello\n" ) or last;
        }
        if( vec( $vin, $fn2, 1 ) ) {
            defined( my $buffer = <$fd2> ) or last;
            print "read: $buffer";
        }
    }
}

__END__

C:\test>junk88
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
read: hello
Terminating on signal SIGINT(2)
read: hello
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