Using the advice I've now simplified:

You've still got the same look-behind typos as described in Re: Looking for a cleaner regex

Guessing at the meaning the look behinds, the list of words is now

.ron steis ste mos es o ó í ué (?<!u)é (?<!st)e (?<!ro)n (?<!.is)s (?<!mos)s (?<!eis)is (?<!ste)is

Eliminating the obviously needless look-behinds , leaving the goofy guesses and guessing again

.ron steis ste mos es o ó í ué é e n (?<!.is)s ## maybe meant (?<!.i)s (?<!mos)s ## maybe meant (?<!mo)s (?<!eis)is ## maybe meant (?<!e)is (?<!ste)is ## maybe meant (?<!ste)is

If my new guess is correct the last 4 needless look behinds can be replaced by "s"

steis .ron ste mos es ué o ó í é e n s

And the single character suffix can be replaced by a char class

steis .ron ste mos es ué [oóíéens]

So there you have it the optimal regex is  qr/( .ron | steis | ste | mos | es | ué | [oóíéens] )$/x


In reply to Re: Looking for a cleaner regex by Anonymous Monk
in thread Looking for a cleaner regex by k-man

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