The problem is when macro: 
/* concatenating with "" ensures that only literal strings are accepte
+d as
 * argument */
#define STR_WITH_LEN(s)  ("" s ""), (sizeof(s)-1)

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is passed a non-literal string (i.e. something which is not quoted, for example the XS_VERSION => 0.011 (via XS_VERSION_BOOTCHECK) which is just a naked 0.011 . Actually this is mentioned in the comments before the macro def (see above code).

By double-quoting contents of -DVERSION and -DXS_VERSION, the command line you pasted succeeds for me:

-DVERSION="\"0.011\"" -DXS_VERSION="\"0.011\""

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The complete command line: 
cc -I/opt/perlbrew/perls/perl-5.18.0/lib/5.18.0/darwin-2level/CORE -DV
+ERSION="\"0.011\"" -DXS_VERSION="\"0.011\"" -c -fno-common -DPERL_DAR
+WIN -fno-strict-aliasing -pipe -fstack-protector -I/usr/local/include
+ -I/opt/local/include -arch x86_64 -framework System -Wa,--noexecstac
+k -I/opt/local/include  -I/opt/X11/include -O3 -o lib/PerlIO/Layers.o
+ lib/PerlIO/Layers.c

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Of course I am not sure if "causes no error" or "succeeds" is the same as "works as intended". But an unquoted 0.011 can be found in the resultant object file:

$ strings lib/PerlIO/Layers.o
0.011
v5.18.0
...

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bliako

In reply to Re: PerlIO::Layers 0.011 fails to build in macOS 10.13.3 by bliako
in thread PerlIO::Layers 0.011 fails to build in macOS 10.13.3 by perlboy_emeritus

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