loadable library and perl binaries are mismatched (got handshake key 0xe280080, needed 0xde00080)

AFAIK this happens when you try to load an XS module that was compiled for a different version of perl. Is Perl v5.16 still installed on that system? Are you sure you've gotten rid of all references to it during the build process of the module as well as when you try to use it later, that is, it's not lurking in PATH, PERL5LIB, etc.?

In reply to Re: Using Perl XS in 5.26 fails with error loadable library and perl binaries are mismatched by haukex
in thread Using Perl XS in 5.26 fails with error loadable library and perl binaries are mismatched by jobinjoseph121

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