Well, you don't tell us anything about the file, but if it's comma delimited, then perhaps this: 
#!/usr/bin/perl -w
use strict;
use warnings;

# create array ref and count
my $matrix=();
my $i=0;

open PROFILES, 'profile/profile.db' or die $!;
while (<PROFILES>) {
  chomp;

  # add array as array ref to array ref
  @{$matrix->[$i]} =  split /\t/; 
  $i++;
}
close(PROFILES);

# access referenced data like this

print $matrix->[1]->[6];

# (7th element of 2nd row generally :)
# should start at 0,0

exit(0);

[download]

cLive ;-)

Update: since you've added more info, I've updated above to reflect your existing code..

--
seek(JOB,$$LA,0);

In reply to (cLive ;-) Re: Fast Matrix Load by cLive ;-)
in thread Fast Matrix Load by Evanovich

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