You can use SpecTcl for desiging your Tk screens. It outputs perl with the help of SpecPerl.
Also I think you can use Glade on Gnome similarly.
Update: When I used SpecTcl it was on Windows and I think it was compiled with SpecPerl - at least I didn't need to download or install anything seperate to get Perl output. I've not used it on Linux.
Update 2: As for the suggestions for wxWindows, I don't think this is suitable if you want a GUI builder. From what I remember there is a GUI builder for wxWindows but it is commercial software.
See the excellent (GUI) Windows Programming FAQ
___ Simon Flack ($code or die)In reply to Re: Perl GUI development...
by $code or die
in thread Perl GUI development...
by johanvdb
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