When I look into the spam I receive, it seems very common that they use X-Reciept: to indicate my real and valid e-mail address, whereas the To: can, as you already pointed out, contain just anything.
Try that and see if it fits your needs.
In reply to Re: Routing mail collected from a POP3 Server
by Biker
in thread Routing mail collected from a POP3 Server
by Anonymous Monk
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