My degree is in theater and writing. It says so right on my resume, but no employer has ever even mentioned this fact in an interview, except to say "cool!" If you have a good resume, can show examples of your work, and demonstrate understanding of the relevant programming concepts, no one will care about what you did in college. I've found that publishing articles and speaking at conferences also lends a lot of credibility to my resume, and those are both pretty easy to do in the Perl community.