My 2 cents on the Ph.D. issue:
Having a Ph.D. in any field is not a drawback, it seems to me. A Ph.D. indicates that you're a very hard worker, very dedicated, and obviously very intelligent--all things that are desirable in any field of work. I think it indicates to an employer than you can learn quickly and thoroughly, so that regardless of what work you've done in the past you can easily acquire the skills required for a new position.
On your resume, or in an interview, you might say something like this: "After receiving my Ph.D., I honed my skills (insert skills here) in the field of bioinformatics, where I (insert important things you have learned or achieved). Now I am seeking a position where I can apply these skills in a more general field, and believe I am well-suited for (position you're applying for)." Be positive, and emphasize how the work you did in your specific field provided you with skills and training you can apply more broadly.
Good luck!
__________
"Abby-somebody. Abby-normal."
Young Frankenstein
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