With that in mind, here is a no-direct-Perl-content recommendation for two Linux Magazine articles on MySQL performance (found via blakem's post about an upcoming Silicon Valley Perl Mongers talk):
There's stuff in here that can save you hours of pouring over the docs.
The author also has a presentation on Building Maintainable and Fault-Tolerant MySQL Applications with Perl.
In reply to OT: MySQL performance when the problem isn't Perl by dws
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