By the way, now that you have the full-featured, maximally
advanced, subtle and idiomatic solution for using variables
with "tr///", here's a simple, direct answer to your opening
question:
eval "\$var =~ tr/$pattern1/$pattern2/";
Note the use of double quotes around the expression, as well
as the backslash in front of "$var". The double quotes will
cause interpolation of variables (variables in the string
will be replaced by their values); the backslash causes the
"$" in "$var" to be passed as a literal, so "eval" gets a string that
begins with the four characters '$var', rather than one that
begins with the current value (contents) of the variable
"$var".
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