Regexp::Subst::Parallel seems to do the trick.

use Regexp::Subst::Parallel;
$_ = "Man Honoured at Harbour Centre by the Lift\n"; 
print;
$_ = subst($_,
        qr/\b(h)arbour\b/i     => '$1arbor',
        qr/\b(h)onour(.*?)\b/i => '$1onor$2',
        qr/\b(c)entre\b/i      => '$1enter',
        qr/\b(L|l)ift\b/       => sub{$_=$_[1]=~/L/?"E":"e";$_."levato
+r"}
      );
print;

__END__

Man Honoured at Harbour Centre by the Lift
Man Honored at Harbor Center by the Elevator
[download]

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