For a second, I thought you were suggesting what I was going to suggest... Close: 

my %repl= ( frog=>"toad", man=>"boy", woman=>"girl" );
$foo =~ s/(frog|man|woman)/$repl($1)/g;

[download]
And you can even build the regex from the keys, if you like: 
my $re= join "|", map quotemeta($_), keys %repl;

[download]
But the original code is probably both faster and simpler. (:

                - tye

In reply to Re^2: multiple (different) substitutions on same $foo (at once) by tye
in thread multiple (different) substitutions on same $foo by jonnyfolk

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