Basically, I run dprofpp -u -p index.pl, and get a random set of functions every time. So one run looks like: 
%Time ExclSec CumulS #Calls sec/call Csec/c  Name
 25.1   0.020  0.070      6   0.0033 0.0116  main::BEGIN
 12.5   0.010  0.010     17   0.0006 0.0006  strict::bits
 12.5   0.010  0.010     24   0.0004 0.0004  Carp::caller_info
 12.5   0.010  0.010      3   0.0033 0.0033  QueryParse::BEGIN
 12.5   0.010  0.020      4   0.0025 0.0050  Storable::BEGIN
 12.5   0.010  0.010      4   0.0025 0.0025  File::Spec::Win32::BEGIN
 0.00   0.000  0.010     13   0.0000 0.0008  strict::import
 0.00   0.000  0.010      3   0.0000 0.0033  CGI::Carp::BEGIN
 0.00   0.000 -0.000     11   0.0000      -  Exporter::import
 0.00   0.000 -0.000      1   0.0000      -  File::Spec::BEGIN
 0.00   0.000 -0.000      5   0.0000      -  Cwd::BEGIN
 0.00   0.000 -0.000      1   0.0000      -  base::BEGIN
 0.00   0.000 -0.000      1   0.0000      -  base::import
 0.00   0.000 -0.000      1   0.0000      -  UNIVERSAL::isa
 0.00   0.000 -0.000      1   0.0000      -  warnings::BEGIN

[download]
While the next one looks like: 
%Time ExclSec CumulS #Calls sec/call Csec/c  Name
 14.3   0.010  0.010      3   0.0033 0.0033  QueryParse::BEGIN
 14.3   0.010  0.010      1   0.0100 0.0100  Exporter::as_heavy
 14.3   0.010  0.010      5   0.0020 0.0020  Cwd::BEGIN
 14.3   0.010  0.010      2   0.0050 0.0050  lib::BEGIN
 14.3   0.010  0.010      2   0.0050 0.0050  Carp::longmess
 14.3   0.010  0.020      4   0.0025 0.0050  File::Spec::Win32::BEGIN
 0.00   0.000  0.060      6   0.0000 0.0100  main::BEGIN
 0.00   0.000 -0.000     13   0.0000      -  strict::import
 0.00   0.000 -0.000     17   0.0000      -  strict::bits
 0.00   0.000  0.020      3   0.0000 0.0066  CGI::Carp::BEGIN
 0.00   0.000  0.010     11   0.0000 0.0009  Exporter::import
 0.00   0.000 -0.000      1   0.0000      -  File::Spec::BEGIN
 0.00   0.000 -0.000      1   0.0000      -  base::BEGIN
 0.00   0.000 -0.000      1   0.0000      -  base::import
 0.00   0.000 -0.000      1   0.0000      -  UNIVERSAL::isa

[download]

I'm assuming that this is because it's not spending enough time in any particular subroutine to really get accurate data, so the top times is more or less random, depending on what else the processor is doing whenever it hits a particular sub?

In reply to Dprofpp, random subroutines by BUU

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