I have recently install mod_perl 2.0 successfully. I am able to run apps successfully but sometimes I have to restart the server in oder to see the changes in the script. I know I'm missing something obvious. Here is the relative portion of my httpd.conf file. My startup script has all the standard modules. 
PerlRequire /usr/local/apache2/conf/startup.pl
Alias /perl/ /usr/local/apache2/perl/
<Location /perl>
        SetHandler perl-script
        PerlResponseHandler ModPerl::Registry
        PerlSendHeader On
        Options +ExecCGI
        PerlSetEnv PERL_DESTRUCT_LEVEL 2
</Location>

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In reply to force to restart server under mod_perl 2.0 by Anonymous Monk

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