First, be sure that you define the FORM tag in your HTML like this:

<form method=post enctype="multipart/form-data"> # multipart/form-data
+ is necessary for uploads
...
<input type="file" name="file"> # This defines an upload field
[download]

Processing the query then should be easy with MIME:Lite:

# Create new Mail object.
my $mail = MIME::LITE->new(
    From => $from,
    To => $to,
    Subject => $subject,
    Type => 'multipart/mixed'
    );

# 'Attach' text to it.
$mail->attach(
    TYPE => 'TEXT',
    DATA => $messagebody
    );

# If we have an attachment, attach it.
if ($q->param("file")) {
    my $upload = $q->upload;
    my $fh = $upload->fh;
    my @data;

    binmode $fh;

    local $_ = '';

    while (read($fh, $_, 1024)) {
        push @data, $_;
    }

    close $fh;

    $mail->attach(
        Data => \@data,
        Filename => $upload->filename,
        Type => $upload->type
        );
}

# Finally, send the mail.
open (MAIL, "| /usr/sbin/sendmail -t -i") or die $!;
$mail->print(\*MAIL);
close MAIL;
[download]

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