I'm actually very surprised at this.. working in a Bioinformatics area.. we've used Perl quite a bit. Granted, we also use other languages such as ASP, ColdFusion, and Java. I still think you use whatever is best for the job. We don't use Perl for our websites, but it's quite useful in other areas. I always thought Perl was a big item for Bioinformatics... maybe the times are changing..