For a slight speed boost, use compiled regular expressions:
my $string = 'eichenbaumschule';
my @query = qw(baum ums eic chu le);
@query = map { qr/($_)/i } @query;

$string =~ s/$_/\U$1/g for @query;

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(I get ~6000 iterations/sec this way vs. ~3000 your way).

Update: Just realized, this is only a factor if you do the same substitutions multiple times in the same program...if you're only doing this once per run, then you may as well do it delirium's way :-)

In reply to Re^2: Regexp string concat by runrig
in thread Regexp string concat by Murcia

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