The first thought that comes to me is to use a repeat statement instead of your "after". Sometimes you just have to use "trial and error" and try alot of different approaches.

my $id; #setup a global for the repeat so you can cancel
             #from anywhere in the script

sub run { #this is called via a button from the GUI
  #Call the Module
 
# update: also try to start the repeat here, before the
# thread start

 $threadRun = Thread -> new (\&printExcel::Edit, $option,$path);
  #print the status
 $id = repeat(5000, \&printStatus() );
}

sub printStatus {
   print "\n\n\n\n\n\nprint status\n";
   #hier hol ich mir den neuen status
   my @NewStatus = &printExcel::GetStatus();
   print "new status: @NewStatus\n";
 
}
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