I have a very similar setting but I use DBD::ODBC instead. Do you define an ODBC source in the control panel of your web server box? This is my connect line:
$dbh = DBI->connect('DBI:ODBC:odbcSourceName', 'username', 'password') + || die $dbh->errstr;
I would recommend that you switch to DBI. Installing DBI and DBD::ODBC is a snap from ppm. Using DBI instead of Win32::ODBC has the advantage of being more portable.

In reply to Re: Win32::ODBC / IIS -- M$ SQL Server 7 on separate machine by gregorovius
in thread Win32::ODBC / IIS -- M$ SQL Server 7 on separate machine by Lexicon

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