Dunno about Win32 (although it's already installed if you're using ActiveState), but it doesn't look like you can't use cpan to install Win32::Serialport, because it has a nonstandard installation instructions. Just do it from the prompt.

In reply to Re^3: installing win32 in perl 5.8.4 by ikegami
in thread installing win32 in perl 5.8.4 by sparkel

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