How log do you spend on a single cat infile >outfile?
Beside that, I think without testing, this is faster as your re: 
 
print OFILE  unless /^(?:K[LM]|P[AM]|S[LZ]|CP|ME|WX|YZ)XX1/;

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Boris

In reply to Re: perl performance vs egrep by borisz
in thread perl performance vs egrep by dba

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