There's an interface to the GNU Scientific Library, Math::Gsl, which has several distribution functions. The underlying C library is (I think; I may be recalling anecdotal evidence here) supposedly fairly good.

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In reply to Re: Fastest way to calculate hypergeometric distribution probabilities (i.e. BIG factorials)? by Fletch
in thread Fastest way to calculate hypergeometric distribution probabilities (i.e. BIG factorials)? by Commander Salamander

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