having recently taken that step myself, some up-to-date tips:
- with debian, perl is all installed automatically and works out-of-the-box;
- even if you're new to the unix world you can soon get the hang of file permissions, but the fun really starts with mysql: that caused me a lot of frustration - you have to change the file ownership (if they're pulled over from windows) to "mysql" as well;
- tried kdevelop as DE for perl and got into a hopeless tangle: it's using a steamroller to crack a nut;
- what I like a lot as my perl DE is SciTe (there's a deb package); there's just a problem under kde with the window frame font sizes (because it's gtk). The solution you'll find on the net of installing gtk2-engines-gtk-qt didn't work (at least the debian package). Scite wouldn't launch afterwards, and I had to deinstall gtk2-engines and delete a couple of *rc config files before it would run again.
..apart from that, all is sweetness and light (...well, most of the time)
good luck.