Yes, and Perl 6 even the special while loop exception is going away. Instead you typically use topicalizers to set $_: 
    given shift {
        do something with $_;
    }

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or 
    for @ARGS {
        do something with $_;
    }

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And in particular, while on a filehandle turns into a (lazy) for: 
    for =$fh {
        do something with $_;
    }

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In general, the only dwimming on void context in the standard Perl 6 dialect will be deciding whether to turn an unthrown exception (aka undef) into a thrown exception because someone forgot to check the return value.

In reply to Re^2: shift doesn't DWIM by TimToady
in thread shift doesn't DWIM by GrandFather

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