Another strong point is TMTOWTDI and that perl has lots of cool built-in's (OP--see perldoc perlrun) for these types of tasks: 
  perl -F, -lane '$x+=$F[99]; END{print $x}' data.txt

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In reply to Re^2: fast way to split and sum an input file by davidrw
in thread fast way to split and sum an input file by egunnar

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