Perhaps some points for clarification:

• Does the same script run OK without the use HTTP::Request line? If so, where on your system is the CGI.pm module found? Is it part of the the/full/dir/path/8080/cgi-bin/usr/local tree?
• What operating system is this on? As was raised in the original question, it's strange that the error in HTTP::Request is reported as http/request.pm. This might suggest there's an issue with case sensitivity and/or tolerance of file names, if this applies to your operating system.
• The symbolic link you tried was from where to where? Also, when you say the contents were subsequently displayed in the browser, was this the contents of the HTTP::Request module, or of the script? If it was the script, there may be a misconfiguration present in your web server; if it's Apache, see the documents on using CGI for suggestions.
• Does the path represented by the/full/dir/path/8080/cgi-bin/usr/local represent a full perl installation, including a perl binary? If so, is this perl compatible with the binary specified by #!/usr/bin/perl used to invoke your script? Is it the same perl that was used (successfully) to test the script from the command line?

As an aside, it probably is a bad idea to have a perl binary beneath the cgi-bin directory, if that is the case; if it's not protected through proper permissions from the outside world, it's not inconceivable that someone might come along and try exploring things like http://your.server/cgi-bin/usr/local/bin/perl, and if they find it ...

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