Since it seems there's no problem with APR in stand-alone mode, it would be good to narrow down why it's interfering with WriteMakefile. A couple of simple possibilities come to mind that would be worth checking:

• Somehow APR affects printing in general. Does the following work in generating a non-zero sized file?

  use APR;
  open(FH, '>test.txt') or die "Cannot open test.txt: $!\n";
  print FH "This is some text\n";
  close(FH);
  [download]

• APR somehow interferes with the arguments passed to WriteMakefile. Does the following print (to STDOUT) the named MakeMaker parameters?

  use ExtUtils::MakeMaker;
  use APR;
  my $r = WriteMakefile(
      NAME         => 'Handel',
      VERSION_FROM => 'lib/Handel.pm',
      AUTHOR       => 'Christopher H. Laco',
      ABSTRACT     => 'Simple ecommerce framework',
  );
  for my $key (qw(NAME VERSION_FROM AUTHOR ABSTRACT)) {
     print "$key -> $r->{$key}\n";
  }
  [download]

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