I think you want: 
$line =~ s/^myword \S+//; # strip myword, a space, and any stretch of 
+non-spaces

[download]
Update: After seeing your clarification, I see that you could have spaces in the comma-separated list. So you'd want: 
$line =~ s/^              #strip, from the beginning of the string,
           myword\s+      #myword, followed by whitespace
           \S+            #followed by non-whitespace
           (?:,\s*\S+)*   #followed by any number of comma, optional w
+hitespace, non-whitespace
          //x;          # update: two slashes are needed here

[download]
Caution: Contents may have been coded under pressure.

In reply to Re: remove specific data from a line by Roy Johnson
in thread remove specific data from a line by Anonymous Monk

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