Are you able to connect to smtp.1and1.com on port 25 from that location? Try this in the cmd shell: 
telnet smtp.1and1.com 25

[download]
I just tested the code from a Win2000 machine with AS perl 5.6.1 and Net::SMTP 2.26 with no issues. I did get that error on a local WinXP machine that cannot make outbound connections to port 25 though.

In reply to Re^2: SMTP Authentication by imp
in thread SMTP Authentication by lv211

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