You said: 
/opt/perl/lib/site_perl/5.8.5/IPC/Run.pm:2613 Cannot flush f=0x805defc

here is line 2513 in my version of Run.pm:

[download]

You are looking at the wrong line. The error message is at 2613, not 2513.

Update: Apparently OP corrected the line number. Unfortunately I don't have a better answer, but good luck!

In reply to Re: Question about the guts of PerlIO and IPC::Run by blahblah
in thread Question about the guts of PerlIO and IPC::Run by OfficeLinebacker

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