I think it means that a server error was encountered. (I actually get '404' - which tells me the file wasn't found.)
There's no such file as 'http://downloads.activestate.com/.../ActivePerl-5.8.8.819-MSWin32-x64-267479.msi'.
Try ' http://downloads.activestate.com/ActivePerl/Windows/5.8/ActivePerl-5.8.8.819-MSWin32-x64-267479.msi'.
Fix the location specified to specify the 64-bit version (x64) instead of the 32-bit version (x86).