Class::DBI::AbstractSearch and Class::DBI::Sweet should let you use -in, as in this untested bit: 
    MyClass->search_where({ col1 => { -in => \@items }})

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Hope this helps.

In reply to Re: How to use the 'in' of SQL using Class::DBI by fenLisesi
in thread How to use the 'in' of SQL using Class::DBI by palette

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