LWP::UserAgent allows you to pass a callback to the request() method, which you can use to stream data into the request.

This is the relevant quote:

$ua->request( $request, $content_cb )

You are allowed to use a CODE reference as content in the request object passed in. The content function should return the content when called. The content can be returned in chunks. The content function will be invoked repeatedly until it return an empty string to signal that there is no more content.

In reply to Re: sending a large file via http by rhesa
in thread sending a large file via http by mifflin

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