How many edits per file? If it's a one off then as you suggest is probably optimum. If there are multiple edits per file, but otherwise a one off then order the edits by file position then run through the source file and output to an edited version applying edits as you go. If this is an ongoing issue use a database (DBI and DBD::SQLite is pretty much a no-brainer to get going).

DWIM is Perl's answer to Gödel

In reply to Re: Updating Binary Files With variable record lengths by GrandFather
in thread Updating Binary Files With variable record lengths by rorokimdim

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