I personally believe that it has already been told you several times to read about binmode: how did it fail to answer your question? Alternatively, with a modern enough perl you can directly use a layer in the open call:

open my $fh, '<:raw', $filename or die "D'Oh! $!\n";

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In reply to Re^5: how to read data for every 280 character ? by blazar
in thread how to read data for every 280 character ? by bh_perl

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