Under the hood OS X is Unix, so you can just use cron. Create a text file called cron.txt that looks something like this: 
23 05 * * * /Users/your_name/bin/perl-script and arguments

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then in a command shell type: 
crontab cron.txt

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Your command should now run at 5:23 AM every day.

For more details check the following man pages from your command shell: 

man cron
man crontab
man 5 crontab # This explains the layout of the cron file

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In reply to Re: Running a perl script automatically on Mac OS X 10.5 by tilly
in thread Running a perl script automatically on Mac OS X 10.5 by Ninth Prince

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