Apparently Visual Studio 2005 .NET Framework2 can "cross-compile to any Windows platform including x86-64 and Itaniuum". The codename to search for is "Whidbey". But I think you might be the first to try it with Perl?

Examine what is said, not who speaks -- Silence betokens consent -- Love the truth but pardon error.
"Science is about questioning the status quo. Questioning authority".
In the absence of evidence, opinion is indistinguishable from prejudice.
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In reply to Re^3: building 64 bit perl on a 32 bit windows machine by BrowserUk
in thread building 64 bit perl on a 32 bit windows machine by Anonymous Monk

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