I faced the same problem using Perl v5.10. You have to specify ORACLE_HOME and NLS_LANG os variables explicitly. See http://www.alexander-foken.de/Censored%20copy%20of%20Oracle%20Troubleshooter%20HOWTO.html#oneoci

In reply to Re^4: Active State Perl 5.10 32bit w/ DBD::Oracle included by Anonymous Monk
in thread Active State Perl 5.10 32bit w/ DBD::Oracle included by chuckd

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