NIST is holding a competition to replace the SHA family of hash functions, and it asked for submissions to be optimized for 64-bit CPU. Unfortunately, it's still very early in the process.

It seems that someone created a module of Digest::Skein, Bruce Schneier and all's submission if you want to take a peek.

In reply to Re: 64-bit digest algorithms by ikegami
in thread 64-bit digest algorithms by BrowserUk

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