Thanks, I'll try DBM::Deep. BTW there were no stealth updates on the first post :-)
UPDATE: Tried DBM::Deep. I'm getting this error:
Use of uninitialized value in -e at /usr/local/share/perl/5.8.8/DBM/Deep/File.pm line 55
Here is the code snippet: 
#!/usr/bin/perl -w
use strict;
use Bio::AlignIO;
use Bio::SeqIO;
use Fcntl qw(O_RDWR O_CREAT);
use DBM::Deep;
require Variation::RecombConfig;
use Variation::Recomb;
use POSIX qw(ceil floor);
use DirHandle;
use File::Temp;
use Data::Dumper;
# do lots of stuff to create a big complex hash, %positions_hash

my $db = DBM::Deep->new( -filename =>"positions.db", pack_size => 'lar
+ge');
$db->import(\%positions_hash);
$db->optimize();

[download]
From the DBM::Deep code it seems that it is not properly creating the new file positions.db. Is there a way around this?

In reply to Re^4: MLDBM tie fails by greigite
in thread MLDBM tie fails by greigite

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