...can lead to "undefined variable"-warnings

Could you provide an example?  I think you're fine as long as you make sure the code has loaded/compiled before you access the variables (using use or require within a BEGIN block): 

---- X.pm ----
$::foo = "foo";
$::bar = "bar";
--------------

#!/usr/bin/perl
use strict;
use warnings;
use X;   # or BEGIN { require X; }

print "$::foo\n";   # no warnings

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In reply to Re^3: Variables in a single file by almut
in thread Variables in a single file by northwestdev

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