Maybe some of the answers in Efficient algorithm needed to split Set::IntSpan objects can be of inspiration to you.

Apart from that I agree with Corion that inversion lists are a good technique for this sort of problem.

Perl 6 - links to (nearly) everything that is Perl 6.

In reply to Re: boolean calculation with very large data by moritz
in thread boolean calculation with very large data by llancet

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