If you downloaded a win32 zip version of openssl (as opposed to installing mingw based version into C:\strawberry\c), you can use 
perl Makefile.PL "LIBS=-LC:\openssl\lib\MinGW -llibeay32 -lssleay32" "
+INC=-IC:\openssl\include"

[download]

In reply to Re^3: Problem installing Crypt::OpenSSL::Random on Win32 by Anonymous Monk
in thread Problem installing Crypt::OpenSSL::Random on Win32 by TedHopp

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